Week 12 
Week 12 | Start (PT) | Visitor | Home | Stadium | TV | |||
| Th | 11/24 | Buffalo | Detroit | Ford Field  | CBS | ||
| Th | 11/24 | NY Giants | Dallas | AT&T Stadium | FOX | ||
| Th | 11/24 | New England | Minnesota | U.S. Bank Stadium | NBC | ||
| Su | 11/27 | Denver | Carolina | Bank of America Stadium | FOX | ||
| Su | 11/27 | Tampa Bay | Cleveland | FirstEnergy Stadium | FOX | ||
| Su | 11/27 | Baltimore | Jacksonville | TIAA Bank Field | CBS | ||
| Su | 11/27 | Houston | Miami | Hard Rock Stadium | CBS | ||
| Su | 11/27 | Chicago | NY Jets | MetLife Stadium | FOX | ||
| Su | 11/27 | Cincinnati | Tennessee | Nissan Stadium | CBS | ||
| Su | 11/27 | Atlanta | Washington | FedEx Field | FOX | ||
| Su | 11/27 | LA Chargers | Arizona | State Farm Stadium | CBS | ||
| Su | 11/27 | Las Vegas | Seattle | Lumen Field | CBS | ||
| Su | 11/27 | LA Rams | Kansas City | GEHA Field at Arrowhead Stadium | FOX | ||
| Su | 11/27 | New Orleans | San Fran | Levi's Stadium | FOX | ||
| Su | 11/27 | Green Bay | Philadelphia | Lincoln Financial Field | NBC | ||
| Mo | 11/28 | Pittsburgh | Indianapolis | Lucas Oil Stadium | ESPN | ||