Week 16 
Week 16 | Start (PT) | Visitor | Home | Stadium | TV | |||
| Th | 12/22 | Jacksonville | NY Jets | MetLife Stadium  | Prime | ||
| Sa | 12/24 | Atlanta | Baltimore | M&T Bank Stadium | FOX | ||
| Sa | 12/24 | Detroit | Carolina | Bank of America Stadium | FOX | ||
| Sa | 12/24 | Buffalo | Chicago | Soldier Field II | CBS | ||
| Sa | 12/24 | New Orleans | Cleveland | FirstEnergy Stadium | CBS | ||
| Sa | 12/24 | Seattle | Kansas City | GEHA Field at Arrowhead Stadium | FOX | ||
| Sa | 12/24 | NY Giants | Minnesota | U.S. Bank Stadium | FOX | ||
| Sa | 12/24 | Cincinnati | New England | Gillette Stadium | CBS | ||
| Sa | 12/24 | Houston | Tennessee | Nissan Stadium | CBS | ||
| Sa | 12/24 | Washington | San Fran | Levi's Stadium | CBS | ||
| Sa | 12/24 | Philadelphia | Dallas | AT&T Stadium | FOX | ||
| Sa | 12/24 | Las Vegas | Pittsburgh | Acrisure Stadium | NFL | ||
| Su | 12/25 | Green Bay | Miami | Hard Rock Stadium | FOX | ||
| Su | 12/25 | Denver | LA Rams | SoFi Stadium | CBS | ||
| Su | 12/25 | Tampa Bay | Arizona | State Farm Stadium | NBC | ||
| Mo | 12/26 | LA Chargers | Indianapolis | Lucas Oil Stadium | ESPN | ||